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Department of Logistics2008-2009 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Engineering metal oxide nanostructures for the fiber optic sensor platform

This paper presents an effective integration scheme of nanostructured SnO2 with the fiber optic platform for chemical sensing applications based on evanescent optical interactions. By using a triblock copolymer as a structure directing agent as the means of nano-structuring, the refractive index of SnO2 is reduced from >2.0 to 1.46, in accordance with effective medium theory for optimal on-fiber integration. Hightemperature stable fiber Bragg gratings inscribed in D-shaped fibers were used to perform real-time characterization of optical absorption and refractive index modulation of metal oxides in response to NH3 from the room temperature to 500°C. Measurement results reveals that the redox reaction of the nanostructured metal oxides exposed to a reactive gas NH3 induces much stronger changes in optical absorption as opposed to changes in the refractive index. Results presented in this paper provide important guidance for fiber optic chemical sensing designs based on metal oxide nanomaterials. © 2014 Optical Society of America

Isolation and antigenicity evaluation of &#946-lactoglobulin from buffalo milk

Buffalo &#946-lactoglobulin in phosphate buffer (0.02 M, pH6.8) was adsorbed on DEAE-Sepharose Fast Flow gel, and eluted with a linear gradient of NaCl (0-0.5 M) in 0.02 M phosphate buffer, pH 6.8. A furtherpurification was performed on Sephadex G-75 gel by loading a concentrated and dialyzed fraction of samples containing buffalo &#946-lactoglobulin from ion-exchange chromatography, and seperating at a flow rate of 0.15 ml/min in 0.02 M phosphate buffer, pH 6.8. The purity of the isolated buffalo &#946-lactoglobulin was above 90% in comparison to the standard bovine &#946-lactoglobulin by SDS-PAGE and IEF-PAGE. The antigencity of the buffalo &#946-lactoglobulin was evualuted by indirect ELISA, Westernblotting and inhibition ELISA with anti-buffalo and anti-bovine &#946-lactoglobulin rabbit serum. The results showed that buffalo &#946-lactoglobulin could be seperated and purified by anion-exchange chromatography combined with gel filtration chromatography, and with a well-preserved antigenicity

The association of HBV core promoter double mutations (A1762T and G1764A) with viral load differs between HBeAg positive and anti-HBe positive individuals: A longitudinal analysis

Background/Aims: Although there have been a few reports regarding the effect of basal core promoter (BCP) double mutations (A1762T and G1764A) on hepatitis B viral loads, the association remains uncertain. We aim to determine the association after controlling for HBeAg - a strong confounding factor.Methods: We selected randomly 190 individuals from a Chinese cohort of 2258 subjects for cross-sectional analysis and 56 of the 190 for longitudinal analysis of viral loads.Results: In multivariable analysis of the cross-sectional data, BCP double mutations are significantly associated with lower viral loads in HBeAg positive subjects but no difference was found in anti-HBe positive subjects. Triple mutations at nucleotide (nt) 1753, 1762 and 1764 and mutations between nt 1809 and 1817, precore stop mutation (nt 1896) and genotype are not associated with viral loads in either HBeAg or anti-HBe positive subjects. Analysis of the longitudinal data yielded similar results to the cross-sectional data. Viral loads differ significantly between individuals infected with wild-type and BCP double mutations prior to HBeAg seroconversion but this difference is lost after seroconversion.Conclusions: BCP double mutations are associated with lower viral loads in HBeAg positive individuals but have no effect on the viral loads of anti-HBe positive individuals. (C) 2008 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved

Design of a Third-party Reverse Logistics Network under a Carbon Tax Scheme

© 2016 Eastern Macedonia and Thrace Institute of Technology. Reverse logistics network involves significant inherent uncertainties, which cannot be completely characterized because of a lack of adequate historical data. In this study, a multi-product and multi-period interval programming model was developed on the basis of partial information to design an effective reverse logistics network. In addition, the trade-offbetween economic benefits and the environmental burdens from carbon emissions was analyzed by considering the effect of a carbon tax scheme on the reverse logistics network design. Through an improved and modified interval linear programming method, the optimal interval solution was obtained with LINGO. Finally, numerical simulations were conducted to explore the effectiveness of the model and the effect of the carbon tax scheme. Results show that the optimal solution of the reverse logistics network design is robust. The effect of the carbon tax scheme is trivial when the carbon tax is low and significant when the carbon tax is high. As carbon tax gradually increases, carbon emissions effectively decrease, but sharply declines the total profit sharply declines. The findings indicate that the proposed model can effectively solve the reverse logistics network design with partial information under a carbon tax scheme

A systematic simulation methodology for LNG ship operations in port waters: a case study in Meizhou Bay

With the increment for liquefied natural gas (LNG) demand, LNG carriers are becoming larger in size. The operational safety of the carriers and the associated terminals is increasingly attracting attention. This is particularly true when a large LNG vessel approaches a terminal, requiring a detailed investigation of ship handling in port waters, especially in certain unusual cases. A full mission simulator provides an effective tool for research and training in operations of both port terminals and ships. This paper presents an experimental design methodology of the full mission simulation. The details as to how the simulation is achieved are described, and the simulation strategies applicable to LNG ships are specified. A typical case study is used to demonstrate and verify the proposed design methodology. The proposed methodology of the full mission simulation provides guidance for port safety research, risk evaluation and seafarer training. © 2017 Institute of Marine Engineering, Science & Technolog

A new hybrid approach to human error probability quantification-applications in maritime operations

Human Reliability Analysis (HRA) has always been an essential research issue in safety critical systems. Cognitive Reliability Error Analysis Method (CREAM), as a well-known second generation HRA method is capable of conducting both retrospective and prospective analysis, thus being widely used in many sectors. However, the needs of addressing the use of a deterministic approach to configure common performance conditions (CPCs) and the assignment of the same importance to all the CPCs in a traditional CREAM method reveal a significant research gap to be fulfilled. This paper describes a modified CREAM methodology based on an Evidential Reasoning (ER) approach and a Decision Making Trial and Evaluation Laboratory (DEMATEL) technique for making human error probability quantification in CREAM rational. An illustrative case study associated with maritime operations is presented. The proposed method is validated by sensitivity analysis and the quantitative analysis result is verified through comparing the real data collected from Shanghai coastal waters. Its main contribution lies in that it for the first time addresses the data incompleteness in HEP, given that the previous relevant studies mainly focus on the fuzziness in data. The findings will provide useful insights for quantitative assessment of seafarers' errors to reduce maritime risks due to human errors

A dual cube hashing scheme for solving LPP integrity problem

In digital forensics, data stored in a hard disk usually contains valuable evidence. Preserving the integrity of the data in the hard disk is a critical issue. A single hash value for the whole hard disk is not appropriate as the investigation may take a long time and latent sector errors (LSEs) (bad sectors due to media imperfection, for example) which cause a sector suddenly unreadable will make the hash value inconsistent. On the other hand, using a hash per sector may need to store a lot of hash values. Previous research has been conducted to use fewer hash values, but can resist some of LSEs to decrease the number of unverifiable sectors even if there are LSEs. This integrity problem is more complicated in the presence of Legal Professional Privileged (LPP) data inside a seized hard disk in digital forensic as the hard disk has to be cloned once seized and the original hard disk will be sealed after cloning. Hash values need to be computed during this cloning process. However, the cloned copy will be returned to the suspect for the deletion of LPP data before the investigator can work on the sanitized copy. Thus, the integrity of unmodified sectors has to be verified using the hash values computed based on the original hard disk. This paper found that existing schemes are not good enough to solve the integrity problem in the presence of both LSEs and deletion of LPP data. We then propose the idea of a "Dual Cube" hashing scheme to solve the problem. The experiments show the proposed scheme performs better than the previous schemes and fits easily into the digital forensic procedure. © 2011 IEEE.published_or_final_versionThe 6th International Workshop on Systematic Approaches to Digital Forensic Engineering In conjunction with the IEEE Security and Privacy Symposium (IEEE/SADFE 2011), Oakland, CA., 26 May 2011. In IEEE/SADFE Proceedings, 2011, p. 1-

Different mechanisms of cis-9,trans-11- and trans-10,cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells

Conjugated linoleic acid (CLA) has been shown to reduce body fat mass in various experimental animals. It is valuable to identify its influence on enzymes involved in energy expenditure, apoptosis, fatty acid oxidation and lipolysis. We investigated isomer-specific effects of high dose, long treatment of CLA (75.4 Μmol/L, 8 days) on protein and gene expression of these enzymes in cultured 3T3-L1 cells. Proteomics identified significant up- or down-regulation of 52 proteins by either CLA isomer. Protein and gene expression of uncoupling protein (UCP) 1, UCP3, perilipin and peroxisome proliferator-activated receptor (PPAR) α increased whereas UCP2 reduced for both CLA isomers. And eight-day treatment of trans-10,. cis-12 CLA, but not cis-9,. trans-11 CLA, significantly up-regulated protein and mRNA levels of PKA (P<05), CPT-1 and TNF-α (P<01). Compared to protein expression, both isomers did not significantly influence the mRNA expression of HSL, ATGL, ACO and leptin. In conclusion, high-dose, long treatment of cis-9,. trans-11 CLA did not promote apoptosis, fatty acid oxidation and lipolysis in adipocytes, but may induce an increase in energy expenditure. trans-10,. cis-12 CLA exhibited greater influence on lipid metabolism, stimulated adipocyte energy expenditure, apoptosis and fatty acid oxidation, but its effect on lipolysis was not obvious. © 2010 Elsevier Inc.postprin